Ring Strain Effects in Enyne-Allene Thermolysis: Switch from the Myers-Saito Reaction to the C2-C6 Biradical Cyclization

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

Michael J. S. Dewar, Eve G. Zoebisch, Eamonn F. Healy et al. · Journal of the American Chemical Society · 1985 · 13.1K citations

Engineering, Altmetric Attention Score, Molecular Biology +18

Design of Enediyne Prodrugs

Martin E. Maier · Synlett · 1995 · 147 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15

DNA-cleavage and antitumor activity of designed molecules with conjugated phosphine oxide-allene-ene-yne functionalities

K.C. Nicolaou, Peter E. Maligres, Jong Heon Shin et al. · Journal of the American Chemical Society · 1990 · 134 citations

Pharmaceutical Science, Bioorganic Chemistry, Antitumor Activity +20

Switching from the Myers Reaction to a New Thermal Cyclization Mode in Enyne-Allenes

Michael Schmittel · Tetrahedron Letters · 1995 · 115 citations

Heterocyclic, Myers Reaction, Physics +6

A Surprising Switch from the Myers–Saito Cyclization to a Novel Biradical Cyclization in Enyne–Allenes: Formal Diels–Alder and Ene Reactions with High Synthetic Potential

Michael Schmittel, Manfred Keller, Susanne Kiau et al. · Chemistry - A European Journal · 1997 · 99 citations

Novel Biradical Cyclization, Derivatives, Engineering +12