The effects of serum complement and its components on the rheumatoid latex fixation test

Abstract

Abstract In the application of the rheumatoid latex fixation test, agglutination may fail to occur in the presence of high concentrations of positive sera in a pattern resembling the prozone of some antigen‐antibody reactions. The serum factors responsible for the prozone phenomenon in the rheumatoid latex fixation test have the properties of the second and fourth components of human complement. In le application del test rheumatoide de fixation a latex, non‐agglutination pote occurrer in le presentia de alte concentrationes de seros positive. Le configuration resimila alora le prozona de certe reactiones de antigeno e anti‐corpore. Le factores seral que es responsabile pro le phenomeno prozonal in le test rheumatoide de fixation a latex ha le proprietates del secunde e del quarte componente de complemento human.