Concepedia

Comparative analysis of phase I and II enzyme activities in 5 hepatic cell lines identifies Huh-7 and HCC-T cells with the highest potential to study drug metabolism

Jie Lin, Lilianna Schyschka, Ruben Mühl‐Benninghaus, Jan Neumann, Liping Hao, Natascha C. Nüssler, Steven Dooley, Liegang Liu, Ulrich Stöckle, Andreas K. Nüssler,

Archives of Toxicology · 2011 · 98 citations · 10 references

DOI

Concepts

References

10

COMPARISON OF PRIMARY HUMAN HEPATOCYTES AND HEPATOMA CELL LINE HEPG2 WITH REGARD TO THEIR BIOTRANSFORMATION PROPERTIES

Stefan Wilkening, Frank Stahl, Augustinus Bader · Drug Metabolism and Disposition · 2003 · 771 citations

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Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

Lei Guo, Stacey L. Dial, Leming Shi et al. · Drug Metabolism and Disposition · 2010 · 341 citations · Full text

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HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro

Marc Lübberstedt, Ursula Müller‐Vieira, Manuela Mayer et al. · Journal of Pharmacological and Toxicological Methods · 2010 · 225 citations

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FLUORESCENCE-BASED ASSAYS FOR SCREENING NINE CYTOCHROME P450 (P450) ACTIVITIES IN INTACT CELLS EXPRESSING INDIVIDUAL HUMAN P450 ENZYMES

M. Teresa Donato, Núria Jiménez, José V. Castell et al. · Drug Metabolism and Disposition · 2004 · 218 citations

, , +17

Comparison of Established Cell Lines at Different Passages by Karyotype and Comparative Genomic Hybridization

Sharon L. Wenger, Jamie R. Senft, Linda M. Sargent et al. · Bioscience Reports · 2004 · 131 citations

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