Phase II Trial of Capecitabine/Irinotecan and Capecitabine/Oxaliplatin in Advanced Gastrointestinal Cancers

Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer

Aimery de Gramont, Arié Figer, Michel Seymour et al. · Journal of Clinical Oncology · 2000 · 3.8K citations

Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

J-Y Douillard, David Cunningham, AD Roth et al. · The Lancet · 2000 · 3.3K citations

Medicine, Pharmacology, Colorectal Cancer +6

Irinotecan plus Fluorouracil and Leucovorin for Metastatic Colorectal Cancer

Leonard B. Saltz, John V. Cox, Charles D. Blanke et al. · New England Journal of Medicine · 2000 · 3K citations · Full text

Phase III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated Fluorouracil–Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer

Sylvie Giacchetti, B Perpoint, Rachid Zidani et al. · Journal of Clinical Oncology · 2000 · 1.4K citations

Comparison of Oral Capecitabine Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Treatment in 605 Patients With Metastatic Colorectal Cancer: Results of a Randomized Phase III Study

Paulo M. Hoff, Rafat Ansari, Gerald Batist et al. · Journal of Clinical Oncology · 2001 · 1.1K citations