Advanced Materials · 2009 · 157 citations · 29 references
EngineeringBioengineeringBiomedical EngineeringBiomaterialsCell AdhesionTissue EngineeringBiomaterials For Tissue EngineeringCell-scaffold InteractionsExtracellular MatrixGelsHydrogelsScaffold DesignCollagen GelsComposite HydrogelsCrosslinkingCrosslinking StrategiesExtracellular Matrix MimicryExtracellular Matrix OrganizationResponsive HydrogelsScaffold Crosslinking
This article describes fabrication of a two-component extracellular matrix (ECM) in which one component acts as a stable structural element and another component gels or dissolves reversibly (a modulatory component). Using a composite collagen-alginate ECM, reversible crosslinking of the alginate (the modulatory component) via application of calcium or citrate modulates cell mobility in a 3D collagen matrix (the structural component).
29
Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
April M. Kloxin, Andrea M. Kasko, Chelsea N. Salinas et al. · Science · 2009 · 1.7K citations · Full text