Clinical and Neuroimaging Characterization of Chinese Dementia Patients with <b><i>PSEN1</i></b> and <b><i>PSEN2</i></b> Mutations

Abstract

PSEN2 mutations are common in the Chinese Han population with a history of AD and FTD. Pathogenic mutations or risk variants in the PSEN2 gene can influence both FTD and AD phenotypic traits and show variations in neuroimaging characterization.