A new antitumor antibiotic, FR-900482: V. Interstrand DNA-DNA cross-links in L1210 cells.

Fractionation of DNA from mammalian cells by alkaline elution

Kurt W. Kohn, Leonard C. Erickson, Regina A. G. Ewig et al. · Biochemistry · 1976 · 832 citations

Life Sciences, Biochemistry, Molecular Biology +14

Qualitative and quantitative aspects of intercalator-induced DNA strand breaks

Warren E. Ross, Daniel Glaubiger, Kurt W. Kohn · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · 1979 · 238 citations

Life Sciences, Cell Biology, Molecular Biology +13

Structure of FR 900482, a novel antitumor antibiotic from a Streptomyces

Itsuo Uchida, Shigehiro Takase, Hiroshi Kayakiri et al. · Journal of the American Chemical Society · 1987 · 155 citations

Pharmacy, Medicinal Chemistry, Microbiology +8

Interactions of mitomycin C with mammalian DNA detected by alkaline elution.

Robert T. Dorr, G. Timothy Bowden, David S. Alberts et al. · PubMed · 1985 · 84 citations

Dentistry, Cell Biology, Molecular Biology +17

A new antitumor antibiotic, FR-900482. II. Production, isolation, characterization and biological activity.

SUMIO KIYOTO, Toshihiro Shibata, Michio Yamashita et al. · The Journal of Antibiotics · 1987 · 80 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6