The nature and mechanism of superoxide production by the electron transport chain: Its relevance to aging

Aging: A Theory Based on Free Radical and Radiation Chemistry

Denham Harman · Journal of Gerontology · 1956 · 8.5K citations

Natural Sciences, Chemistry, Aging +16

Hydroperoxide metabolism in mammalian organs.

B Chance, Helmut Sies, A Boveris · Physiological Reviews · 1979 · 5.8K citations

Life Sciences, Biochemistry, Physiology +14

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

Alberto Boveris, Britton Chance · Biochemical Journal · 1973 · 2.6K citations · Full text

Life Sciences, Biochemistry, Bioenergetics +16

Reactivity of HO2/O−2 Radicals in Aqueous Solution

Benon H. J. Bielski, Diane E. Cabelli, Ravindra L. Arudi et al. · Journal of Physical and Chemical Reference Data · 1985 · 2.1K citations

Natural Sciences, Chemistry, Chemical Kinetics +15

The Biologic Clock: The Mitochondria?

Denham Harman · Journal of the American Geriatrics Society · 1972 · 2K citations

Life Sciences, Biology, Physiology +17