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Development of a gas chromatography–mass spectrometry method for the analysis of aminoglycoside antibiotics using experimental design for the optimisation of the derivatisation reactions

BiochemistryAntibioticsMedicineBioanalysisMass SpectrometryAnalytical ChemistryAntibacterial AgentAntimicrobial ChemotherapyAntimicrobial PharmacokineticsExperimental DesignAminoglycoside AntibioticsDerivatisation ReactionsPharmacologyPharmaceutical ChemistryAntimicrobial ResistanceChromatographyDrug Analysis