<i>Second Prize:</i> Comprehensive Proteomic Analysis of Human Calcium Oxalate Monohydrate Kidney Stone Matrix

Abstract

SDS reducing buffer was efficient at solubilizing proteins from stone matrix for further MS-based proteomic analysis. A variety of cellular, structural, and plasma proteins comprise COM stone matrix. Several of the stone proteins are involved in cell injury pathways, which suggests that inflammation plays a role in human COM stone formation.