PAINS in the Assay: Chemical Mechanisms of Assay Interference and Promiscuous Enzymatic Inhibition Observed during a Sulfhydryl-Scavenging HTS

Jayme L. Dahlin, J. Willem M. Nissink, Jessica M. Strasser, +5

Journal of Medicinal Chemistry

Lead CompoundsChemical MechanismsDrug TargetChemical BiologyPharmaceutical Chemistry +21

Reduction in Antioxidant Defenses may Contribute to Ochratoxin A Toxicity and Carcinogenicity

Christophe Cavin, Thierry Delatour, Maricel Marin‐Kuan, +11

Toxicological Sciences

ImmunotoxicologyLipid PeroxidationCell DeathRedox BiologyToxicological Mechanism +15

Functional, structural, and chemical changes in myosin associated with hydrogen peroxide treatment of skeletal muscle fibers

Ewa Próchniewicz, Dawn A. Lowe, Daniel Spakowicz, +5

American Journal of Physiology-Cell Physiology

Muscle FunctionEngineeringCytoskeletonMechanotransductionCellular Physiology +15

Proteome of Human Calcium Kidney Stones

Benjamin K. Canales, Lorraine Anderson, LeeAnn Higgins, +5

Urology

MedicinePhysiologyChronic Kidney DiseaseProteomicsNephrology +2

Re-evaluation of the Role of Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP) in Cellular Calcium Signaling

Yaping Lin-Moshier, Peter Sebastian, LeeAnn Higgins, +3

Journal of Biological Chemistry

Lymphokine-Activated Killer T-Cell-Originated Protein Kinase Phosphorylation of Histone H2AX Prevents Arsenite-Induced Apoptosis in RPMI7951 Melanoma Cells

Tatyana A. Zykova, Feng Zhu, Chengrong Lu, +5

Clinical Cancer Research

Relative Quantification: Characterization of Bias, Variability and Fold Changes in Mass Spectrometry Data from iTRAQ-Labeled Peptides

Douglas W. Mahoney, Terry M. Therneau, Carrie J. Heppelmann, +7

Journal of Proteome Research

Biological Mass SpectrometryPathologyItraq-labeled PeptidesMass Spectrometry DataProteomic Technology +20

Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis

Salmaan Khan, Edith E. Wollaston‐Hayden, Todd W. Markowski, +2

Journal of Lipid Research

Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism

Charles P. Najt, Santosh Adhikari, Timothy D. Heden, +13

Cell Reports

Mitochondrial BiologyFatty Liver DiseaseNumerous OrganellesOxidative StressFatty Acids +17

Protein relative abundance patterns associated with sucrose-induced dysbiosis are conserved across taxonomically diverse oral microcosm biofilm models of dental caries

Joel Rudney, Pratik Jagtap, Cavan Reilly, +5

Microbiome