The efficient consecutive β-carboxylation and α-alkylation of cyclic α,β-enones; a new route to sarkomycin

Synthetic methods using α-heterosubstituted organometallics

A. Krief · Tetrahedron · 1980 · 299 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Conjugate addition of trimethysilyllithium. A preparation of 3-silyl ketones

W. Clark Still · The Journal of Organic Chemistry · 1976 · 197 citations

Natural Sciences, Chemistry, Analytical Chemistry +7

Stannylation/destannylation. New syntheses of carbonyl compounds via organotin intermediates

W. Clark Still · Journal of the American Chemical Society · 1977 · 176 citations

Natural Sciences, Chemistry, Inorganic Chemistry +4

Prostaglandin synthesis. 10. An extremely short way to prostaglandins

Masaaki Suzuki, Atsushi Yanagisawa, R. Noyori · Journal of the American Chemical Society · 1985 · 127 citations

Natural Sciences, Chemistry, Pharmacology +8

Alkylation of enolate ions generated regiospecifically via organocopper reactions. Synthesis of decalin sesquiterpene valerane and of prostaglandin model systems

Gary H. Posner, Jeffrey Sterling, Charles E. Whitten et al. · Journal of the American Chemical Society · 1975 · 120 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9