Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/β-catenin pathway

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

John Brognard, Amy S. Clark, Yucheng Ni et al. · PubMed · 2001 · 892 citations

Medicine, Cancer Biology, Oncology +17

Curcumin regulates miR-21 expression and inhibits invasion and metastasis in colorectal cancer

Giridhar Mudduluru, Jonahunnatha Nesson George-William, Santoshi Muppala et al. · Bioscience Reports · 2010 · 331 citations · Full text

Medicine, Molecular Biology, Oncology +16

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)

SONG-SHEI LIN, Kuang‐Chi Lai, Shu‐Chun Hsu et al. · Cancer Letters · 2009 · 254 citations

Medicine, Oncology, Pharmacology +14

Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways.

Shin‐Hwar Wu, Liang-Wen Hang, Jai‐Sing Yang et al. · PubMed · 2010 · 241 citations

Life Sciences, Oncology, Pharmacology +17

Curcumin Inhibits Lung Cancer Cell Invasion and Metastasis through the Tumor Suppressor HLJ1

Huei‐Wen Chen, Jen‐Yi Lee, Jiying Huang et al. · Cancer Research · 2008 · 221 citations · Full text

Medicine, Oncology, Pharmacology +15