Polylysine-based transfection systems utilizing receptor-mediated delivery

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

Pharmacy, Biotechnology, Pharmaceutics +17

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Joseph Zabner, A Fasbender, Tom Moninger et al. · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

Jean Haensler, Francis C. Szoka · Bioconjugate Chemistry · 1993 · 1.2K citations

Life Sciences, Biotechnology, Molecular Biology +17

Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.

Ralph L. Brinster, H Y Chen, Myrna E. Trumbauer et al. · Proceedings of the National Academy of Sciences · 1985 · 1.1K citations · Full text

Life Sciences, Biotechnology, Genetics +15

High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

Mario R. Capecchi · Cell · 1980 · 1K citations

Life Sciences, Biotechnology, Molecular Biology +10