Journal of Carbohydrate Chemistry · 1988 · 45 citations · 21 references
Natural SciencesChemistryCarbohydrate ChemistryOrganic ChemistryCarbohydrate SynthesisCatalytic MaterialsGlycan BiosynthesisHeterocyclic ChemistryO-linked GlycosylationOrganic SynthesisGlycal ChemistryGlycan Building Block SynthesisGlycan SynthesisMild Reaction ConditionsO-linked Glycan SynthesisOne-pot Oligosaccharide Synthesis
Abstract Potassium-graphite laminate (C8K) in oxolane almost instantaneously converts O-alkyl and O-aUcylidene pyranosyl and furanosyl chlorides under extremely mild conditions and in high yields into pyranoid and furanoid glycals, which in the presence of an additional mole of C8K, are efficiently O-alkylated or O-silylated In easily conducted one-pot reactions.
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