Nucleic Acids Research · 1983 · 142 citations · 22 references
The complete nucleotide sequence of the rat 18S ribosomal RNA gene has been determined. A comparison of the rat 18S ribosomal RNA gene sequence with the known sequences of yeast and frog revealed three conserved (stable) regions, two unstable regions, and three large inserts. (A,T) leads to (G,C) changes were more frequent than (G,C) leads to (A,T) changes for three comparisons (yeast leads to frog, frog leads to rat, and yeast leads to rat). GC pairs were inserted preferentially over AT pairs for the same three comparisons. These two factors contribute to the progressively higher GC content of 18S ribosomal RNA of yeast, frog, and rat.
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A new method for sequencing DNA.
Allan M. Maxam, Wendy V. Gilbert · Proceedings of the National Academy of Sciences · 1977 · 8K citations · Full text
Dna, Radioactive Bands, Engineering +18
Conservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells
Otto Hagenbüchle, Melvin Santer, Joan A. Steitz et al. · Cell · 1978 · 427 citations