Oral supplementation of piperine leads to altered phase II enzymes and reduced DNA damage and DNA-protein cross links in Benzo(a)pyrene induced experimental lung carcinogenesis

Glutathione S-Transferases

William H. Habig, M. Pabst, William B. Jakoby · Journal of Biological Chemistry · 1974 · 18.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

A simple technique for quantitation of low levels of DNA damage in individual cells

Narendra P. Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research · 1988 · 10.8K citations · Full text

Pharmacy, Cell Biology, Molecular Biology +10

Preferential Formation of Benzo[ <i>a</i> ]pyrene Adducts at Lung Cancer Mutational Hotspots in <i>P53</i>

Mikhail F. Denissenko, Annie Pao, Moon‐shong Tang et al. · Science · 1996 · 1.7K citations

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Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity.

Ann M. Benson, Markus J. Hunkeler, Paul Talalay · Proceedings of the National Academy of Sciences · 1980 · 752 citations · Full text

Life Sciences, Biochemistry, Toxicology +13

Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages—Induction by multiple nonphagocytic stimuli

Edgar Pick, Yona Keisari · Cellular Immunology · 1981 · 488 citations

Life Sciences, Cell Biology, Immunology +16