Syntheses of (+)-Cytisine, (−)-Kuraramine, (−)-Isokuraramine, and (−)-Jussiaeiine A

Abstract

Total syntheses of (+)-cytisine, (-)-kuraramine, (-)-isokuraramine, and (-)-jussiaeiine A were achieved via a samarium diiodide-promoted reductive deamination reaction, followed by simultaneous recyclization of a proline derivative to give the corresponding delta-lactam derivative, as a key step.