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An alternative synthesis of (+)-biotin from carbohydrate, a formal synthesis of (+)-biotin from d-glucosamine.
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1978
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BiosynthesisBioorganic ChemistryGlycosylationBiochemistryMedicineNatural SciencesGlycobiologyBioconjugationAlternative SynthesisNatural Product BiosynthesisPolysaccharideCarbohydrate-protein InteractionPharmacologyFormal SynthesisSynthetic ChemistryBiomolecular EngineeringNatural Product Synthesis
(+)-Biotin was synthesized from D-glucosamine in a sequence of 13 reactions.