Concepedia

6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid mimics active conformation of tyrosine in opioid peptides

Emanuela Sperlinga, Piotr Kossoń, Z. Urbańczyk-Lipkowska, Giuseppe Ronsisvalle, Daniel B. Carr, Andrzej W. Lipkowski

Bioorganic & Medicinal Chemistry Letters · 2005 · 11 citations · 8 references

DOIFull text

Open access

Concepts

References

8

Topographical requirements for delta opioid ligands: Common structural features of dermenkephalin and deltorphin

Aleksandra Misicka, Andrzej W. Lipkowski, Róbert Horváth et al. · Life Sciences · 1992 · 79 citations

, , +16

Conformational restriction of Tyr and Phe side chains in opioid peptides: Information about preferred and bioactive side‐chain topology

Dirk Tourwé, Anne Frycia, Peg Davis et al. · Biopolymers · 1996 · 75 citations

, , +17

Peptides as receptor selectivity modulators of opiate pharmacophores

Andrzej W. Lipkowski, S. William Tam, Philip S. Portoghese · Journal of Medicinal Chemistry · 1986 · 62 citations · Full text

, , +13

Syntheses of 6-oxodecahydroisoquinoline-3-carboxylates. Useful intermediates for the preparation of conformationally defined excitatory amino acid antagonists

Paul L. Ornstein, M. Brian Arnold, Nancy K. Augenstein et al. · The Journal of Organic Chemistry · 1991 · 43 citations

, , +7

A three-dimensional model of the δ-opioid pharmacophore: Comparative molecular modeling of peptide and nonpeptide ligands

Mark D. Shenderovich, Subo Liao, Xinhua Qian et al. · Biopolymers · 2000 · 39 citations

, , +17