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CD28 costimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases

AllergyAutoimmune DiseaseHuman DiseasesAdaptive Immune SystemImmunologyImmunodominanceCd28 CostimulationElispot AssayAutoimmunityAntigen ProcessingCd4 T Cell ResponsesImmunotherapyMedicineImmunological MemoryImmunological Biomarkers