Concepedia

An Efficient Oxidation of 1,4-Dihydropyridines Using Aqueous<i>tert.</i>-Butylhydroperoxide

Subhash P. Chavan, Shubhada W. Dantale, Uttam R. Kalkote, V. S. Jyothirmai, Rajendra K. Kharul

Synthetic Communications · 1998 · 41 citations · 10 references

DOI

Concepts

Abstract

Abstract Aromatization of 4-substituted 1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate using aqueous tert.-butylhydroperoxide in 74–87% yield has been achieved.

References

10

Oxidation of 4-aryl- and 4-alkyl-substituted 2,6-dimethyl-3,5-bis(alkoxycarbonyl)-1,4-dihydropyridines by human liver microsomes and immunochemical evidence for the involvement of a form of cytochrome P-450

Ronald Boecker, F. Peter Guengerich · Journal of Medicinal Chemistry · 1986 · 323 citations

The Hantzsch Reaction. I. Oxidative Dealkylation of Certain Dihydropyridines

Bernard Loev, Kenneth M. Snader · The Journal of Organic Chemistry · 1965 · 258 citations

, , +12

Rapid, High-Yield Oxidation of Hantzsch-Type 1,4-Dihydropyridines with Ceric Ammonium Nitrate

Jürg R. Pfister · Synthesis · 1990 · 137 citations

, , +8

A novel application of the oxidizing properties of pyridinium chlorochromate : aromatization of Hantzsch 1,4-dihydropyridines

Jean Jacques Vanden Eynde, Annie Mayence, A. Maquestiau · Tetrahedron · 1992 · 128 citations

, , +6

Potassium permanganate, a versatile reagent for the aromatization of Hantzsch 1,4-dihydropyridines

Jean Jacques Vanden Eynde, Rita D'Orazio, Yves Van Haverbeke · Tetrahedron · 1994 · 111 citations

, , +6