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Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with In Vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785)

Vivo ActivitySignal TransductionSignaling PathwayIrreversible InhibitionMedicineReceptor Tyrosine KinaseReceptor (Biochemistry)PharmacotherapyCell GrowthPharmacologyCell BiologyCell SignalingDrug Discovery