Concepedia

Selective targeting of the nuclear factor-κB pathway enhances tumor necrosis factor–related apoptosis-inducing ligand-mediated pancreatic cancer cell death

Robert Paul Thomas, Buckminster Farrow, Sung‐Hoon Kim, Michael J. May, Mark R. Hellmich, B. Mark Evers

Surgery · 2002 · 62 citations · 21 references

Concepts

Life SciencesCancer BiologyOncologyApoptosisInflammationMolecular OncologyApoptosis In CancerApoptotic Signal TransductionApoptotic SignalingCell DeathDeath ReceptorsPancreatic CancerApoptosis Signaling In CancerCell Death Signaling PathwaysNuclear Factor Kappa B ActivationNuclear Factor Kappa B InhibitionTargetingTumor Necrosis Factor-mediated ApoptosisTumor Necrosis Factor-related Apoptosis-inducing Ligand Receptors

References

21

Cancer Statistics, 2002

Ahmedin Jemal, Anish Thomas, Thomas S. Murray et al. · CA A Cancer Journal for Clinicians · 2002 · 2.9K citations · Full text

Medicine, Demography, Oncology +17

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

Cun-Yu Wang, Marty W. Mayo, Albert S. Baldwin · Science · 1996 · 2.6K citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

James P. Sheridan, Scot A. Marsters, Robert Pitti et al. · Science · 1997 · 1.7K citations

Life Sciences, Cell Biology, Molecular Biology +17

The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-x <sub>L</sub>

Cailin Chen, Leonard C. Edelstein, Céline Gélinas · Molecular and Cellular Biology · 2000 · 751 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +15

Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex

Michael J. May, Fulvio D’Acquisto, Lisa A. Madge et al. · Science · 2000 · 681 citations

Medicine, Molecular Biology, Pharmacology +17