Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber.

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

Alfred W. Alberts, J Chen, G. W. Kuron et al. · Proceedings of the National Academy of Sciences · 1980 · 1.6K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

Akira Endo, Masao Kuroda, Yoshio Tsujita · The Journal of Antibiotics · 1976 · 954 citations · Full text

Life Sciences, Microbiology, Drug Discovery +2

Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activity

Akira Endo, Masao Kuroda, Kazuhiko Tanzawa · FEBS Letters · 1976 · 802 citations

Life Sciences, Biochemistry, Pharmacology +16

Monacolin K, a new hypocholesterolemic agent produced by a Monascus species.

Akira Endo · The Journal of Antibiotics · 1979 · 670 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +11

Crystal and molecular structure of compactin, a new antifungal metabolite from Penicillium brevicompactum

A. G. BROWN, Terry C. Smale, Trevor J. King et al. · Journal of the Chemical Society Perkin Transactions 1 · 1976 · 360 citations

Life Sciences, Biochemistry, Microbiology +17