Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Medicine, Cardiology, Molecular Genetics +16

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

Matthew C. Trudeau, Jeffrey W. Warmke, Barry Ganetzky et al. · Science · 1995 · 1.2K citations

Natural Sciences, Genetics, Molecular Genetics +17

A structural basis for drug-induced long QT syndrome

John S. Mitcheson, Jun Chen, Monica Lin et al. · Proceedings of the National Academy of Sciences · 2000 · 937 citations

Medicine, Cardiology, Pharmacology +17

The inward rectification mechanism of the HERG cardiac potassium channel

Paula L. Smith, Thomas Baukrowitz, Gary Yellen · Nature · 1996 · 760 citations

Natural Sciences, Biophysics, Cardiology +13

Fast inactivation causes rectification of the IKr channel.

Peter Spector, Mark Curran, Anruo Zou et al. · The Journal of General Physiology · 1996 · 397 citations · Full text

Natural Sciences, Biophysics, Physiology +17