Concepedia

Coupling of agonist binding to channel gating in the GABAA receptor

Thomas L. Kash, Andrew Jenkins, Jill C. Kelley, James R. Trudell, Neil L. Harrison

Nature · 2003 · 315 citations · 26 references

DOI

Concepts

References

26

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Katjuša Brejc, Willem J. van Dijk, Remco V. Klaassen et al. · Nature · 2001 · 1.8K citations

, , +17

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

Peter R. Schofield, Mark G. Darlison, Norihisa Fujita et al. · Nature · 1987 · 1.6K citations

, , +16

Disulphide bridges in globular proteins

Janet M. Thornton · Journal of Molecular Biology · 1981 · 776 citations

, , +14

First genetic evidence of GABAA receptor dysfunction in epilepsy: a mutation in the γ2-subunit gene

Stéphanie Baulac, Gilles Huberfeld, Isabelle Gourfinkel‐An et al. · Nature Genetics · 2001 · 766 citations

, , +16

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

Gideon Schreiber, Alan R. Fersht · Journal of Molecular Biology · 1995 · 573 citations

, , +15