Concepedia

Geranylgeranylacetone protects against acetaminophen-induced hepatotoxicity by inducing heat shock protein 70

Tadashi Nishida, Tatsuya Matsura, Junya Nakada, Aki Togawa, Masachika Kai, Isao Sumioka, Yukari Minami, Yoshimi Inagaki, Yuichi Ishibe, Hisao Ito,

Toxicology · 2005 · 35 citations · 44 references

Concepts

PharmacyPharmacologyToxicologyHepatotoxicologyMolecular PharmacologyMolecular ToxicologyApoptosis In Liver ToxicityBiomarkers Of Liver InjuryChemical-induced HepatotoxicityHepatic ToxicityHepatotoxicity MechanismsAcetaminophen-induced Liver NecrosisHeat Shock FactorsHeat Shock ResponseHepatocellular Liver InjuryHepatotoxic Mechanisms

References

44

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Marion M. Bradford · Analytical Biochemistry · 1976 · 211.2K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

ACETAMINOPHEN-INDUCED HEPATIC NECROSIS. II. ROLE OF COVALENT BINDING IN VIVO

David J. Jollow, John R. Mitchell, William Z. Potter et al. · Journal of Pharmacology and Experimental Therapeutics · 1973 · 1.2K citations

Veterinary Medicine, Pharmacology, Toxicology +17

Efficacy of Oral N-Acetylcysteine in the Treatment of Acetaminophen Overdose

Martin J. Smilkstein, Gary L. Knapp, Kenneth Kulig et al. · New England Journal of Medicine · 1988 · 1.1K citations

Pharmacy, Pharmacology, Toxicology +17

N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen.

David C. Dahlin, Gerald T. Miwa, Albert Lu et al. · Proceedings of the National Academy of Sciences · 1984 · 1.1K citations

Medicine, Pharmacology, Toxicology +16