Comparison of Continuous Epidural Infusion of Fentanyl-Bupivacaine and Morphine-Bupivacaine in Management of Postoperative Pain

R. Fischer, T. R. Lubenow, A. Liceaga, Robert J. McCarthy, Anthony D. Ivankovich, Brett B. Gutsche, Theodore G. Cheek

Obstetric Anesthesia Digest · 1989 · 18 citations · 0 references

Abstract

One hundred and seven (107) gravidae underwent scheduled cesarean section with epidural block using 2% lidocaine with 1:200,000 epinephrine. Thereafter they were randomly divided into 2 groups to receive one of two epidural solutions by infusion. Each solution consisted of 0.1% bupivacaine containing either 0.01% morphine or 0.001% fentanyl. The infusion was begun with a 5 ml bolus followed by 5 ml/h via an infusion pump. Additional pain relief was provided, if needed, by IM meperidine and oral benztropine. Diphenhydramine intravenously was given for relief of nausea. Assessment was made of pain relief (by means of a visual analog scale), requirement for supplemental medication for pain, nausea or pruritus relief, presence of sensory or motor block and changes in mental status or respiratory stability. Data were recorded every 4 hours for 24 hours at which time the epidural catheter was withdrawn.