Concepedia

Type I interferon‐associated cytotoxic inflammation in lichen planus

Joerg Wenzel, Marina Scheler, Julia Proelss, Thomas Bieber, Thomas Tüting

Journal of Cutaneous Pathology · 2006 · 125 citations · 23 references

DOI

Abstract

Our observations support the hypothesis that lesional type I IFNs produced by pDCs plays an important role in chronic cytotoxic inflammation of LP by recruiting cytotoxic effector lymphocytes via IP10/CXCR3 interactions.

References

23

IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex

Sergei V. Kotenko, Grant Gallagher, Vitaliy V. Baurin et al. · Nature Immunology · 2002 · 1.8K citations

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Plasmacytoid Dendritic Cells (Natural Interferon- α/β-Producing Cells) Accumulate in Cutaneous Lupus Erythematosus Lesions

Lóránt Farkas, Klaus Beiske, Fridtjof Lund‐Johansen et al. · American Journal Of Pathology · 2001 · 721 citations · Full text

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Ultraviolet radiation–induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus

Stephan Meller, Franziska Winterberg, Michel Gilliet et al. · Arthritis & Rheumatism · 2005 · 239 citations

Enhanced type I interferon signalling promotes Th1‐biased inflammation in cutaneous lupus erythematosus

Joerg Wenzel, Eva Wörenkämper, S Freutel et al. · The Journal of Pathology · 2005 · 239 citations

IFN-α2a induces IP-10/CXCL10 and MIG/CXCL9 production in monocyte-derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells

Elisabetta Padovan, Giulio C. Spagnoli, Maria Ferrantini et al. · Journal of Leukocyte Biology · 2002 · 230 citations

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