Effects of repeated psychostimulant administration on the prodynorphin system activity and kappa opioid receptor density in the rat brain

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

Charles Chavkin, Iain F. James, Avram Goldstein · Science · 1982 · 1.2K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain

Alfred Mansour, Henry Khachaturian, M. E. Suzanne Lewis et al. · Pain · 1988 · 980 citations

Medicine, Neurobiology, Neuroscience +10

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

G. Di Chiara, Assunta Impérato · Journal of Pharmacology and Experimental Therapeutics · 1988 · 922 citations

Medicine, Neuroscience, Pharmacology +17

Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain.

W. Scott Young, T I Bonner, Mark R. Brann · Proceedings of the National Academy of Sciences · 1986 · 744 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

The Effects of Opioid Peptides on Dopamine Release in the Nucleus Accumbens: An In Vivo Microdialysis Study

Rainer Spanagel, Albert Herz, Toni S. Shippenberg · Journal of Neurochemistry · 1990 · 541 citations

Medicine, Neuroscience, Pharmacology +17