Population pharmacokinetic and pharmacodynamic analyses of teicoplanin in Japanese patients with systemic MRSA infection

Ryuichi Ogawa, Seiichi Kobayashi, Yuki Sasaki, Mizue Makimura, Hirotoshi Echizen

International Journal of Clinical Pharmacology and Therapeutics · 2013 · 32 citations · 0 references

Abstract

We propose that an extended loading regimen (400 mg every 12 hours for the first 5 doses) would be a treatment option to maximize the therapeutic effects of teicoplanin in patients with systemic MRSA infection.