Fumiquinazolines A–G, novel metabolites of a fungus separated from a Pseudolabrus marine fish

Abstract

Seven new fumiquinazolines (FQs) A–G have been isolated from a strain of Aspergillus fumigatus originally separated from the marine fish Pseudolabrus japonicus, and their stereostructures and conformations have been established on the basis of spectral and X-ray analyses and some chemical transformations. All the compounds exhibited moderate cytotoxicity against cultured P388 cells.