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Assessment of a radioisotopic assay for vitamin B <sub>12</sub> using an intrinsic factor preparation with R proteins blocked by vitamin B <sub>12</sub> analogues

Barbara J. Bain, G N Broom, Jackie Woodside, R. A. C. Litwinczuk, S. N. Wickramasinghe

Journal of Clinical Pathology · 1982 · 26 citations · 9 references

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Abstract

A competitive protein binding radioassay kit for serum vitamin B(12) has been assessed. Precision, linearity, sensitivity, and specificity have been found to be satisfactory. Falsely-normal assay results in patients with vitamin B(12) deficiency have not been observed.

References

9

Cobalamin Analogues Are Present in Human Plasma and Can Mask Cobalamin Deficiency because Current Radioisotope Dilution Assays Are Not Specific for True Cobalamin

J F Kolhouse, Haruki Kondo, Nancy C. Allen et al. · New England Journal of Medicine · 1978 · 263 citations

, , +12

Evidence That Some Patients with Pernicious Anemia Are Not Recognized by Radiodilution Assay for Cobalamin in Serum

Bernard A. Cooper, Victor Whitehead · New England Journal of Medicine · 1978 · 87 citations

, , +14

The Use of Chicken Serum for Measurement of Serum Vitamin B<sub>12</sub> Concentration by Radioisotope Dilution: Description of Method and Comparison with Microbiological Assay Results

Ralph Green, Peter Newmark, Arturo M. Mussos et al. · British Journal of Haematology · 1974 · 73 citations

, , +10

A fault in the design of the deoxyuridine suppression test

S. N. Wickramasinghe, Jimmy Saunders · Clinical & Laboratory Haematology · 2008 · 18 citations

, , +1

Forms of vitamin B12 in radioisotope dilution assays.

J. A. Begley, Charles A. Hall · Journal of Clinical Pathology · 1981 · 15 citations · Full text

, , +12