Analysis and origins of the human and mouse RNase L genes: mediators of interferon action

Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

Gregory E. Hannigan, Chungyee Leung-Hagesteijn, L Fitz-Gibbon et al. · Nature · 1996 · 1.1K citations

Anchorage-dependent Growth, Developmental Biology, Signal Transduction +11

The Transmembrane Kinase Ire1p Is a Site-Specific Endonuclease That Initiates mRNA Splicing in the Unfolded Protein Response

Carmela Sidrauski, Peter Walter · Cell · 1997 · 898 citations · Full text

Transmembrane Kinase Ire1p, Protein Folding, Natural Sciences +9

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

Witoon Tirasophon, Ajith Welihinda, Randal J. Kaufman · Genes & Development · 1998 · 897 citations · Full text

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

Xuya Wang · The EMBO Journal · 1998 · 787 citations · Full text

Reductive Stress, Signal Transduction, Molecular Regulation +10

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

A. Zhou · The EMBO Journal · 1997 · 561 citations · Full text

Mice Devoid, Immunology, Cell Death +8