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STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression

Signal TransductionSignaling PathwayEpigenetic RegulationMedicineReceptor Tyrosine KinaseNpm1-alk ExpressionTumor SuppressorSystems BiologyCancer BiologyCell BiologyCell SignalingTumor BiologyTyrosine Kinase Npm1-alk