Concepedia

6β-Hydroxy-Δ <sup>1</sup> -Tetrahydrocannabinol Synthesis and Biological Activity

Zvi Ben‐Zvi, Raphael Mechoulam, H. Edery, G. PORATH

Science · 1971 · 29 citations · 15 references

DOI

Concepts

Abstract

6beta-Hydroxy-delta(1)-tetrahydrocannabinol, a metabolite of delta(1)-tetrahydrocannabinol has been synthesized from delta(6)-tetrahydrocannabinol. It shows high tetrahydrocannabinol-type activity in rhesus monkeys. The implications of this funding are discussed.

References

15

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

Yehiel Gaoni, Raphael Mechoulam · Journal of the American Chemical Society · 1964 · 2.4K citations

, , +6

Isolation and structure of .DELTA.+- tetrahydrocannabinol and other neutral cannabinoids from hashish

Yechiel Gaoni, Raphael Mechoulam · Journal of the American Chemical Society · 1971 · 365 citations

, , +8

Chemical Basis of Hashish Activity

Raphael Mechoulam, Arnon Shani, H. Edery et al. · Science · 1970 · 330 citations

, , +9

Marihuana: Studies on the Disposition and Metabolism of Delta-9-Tetrahydrocannabinol in Man

Louis Lemberger, Stephen D. Silberstein, Julius Axelrod et al. · Science · 1970 · 206 citations

, , +10

Psychopharmacological activity of the active constituents of hashish and some related cannabinoids

Yona Grunfeld, H. Edery · Psychopharmacology · 1969 · 183 citations

, , +11