Design of multi-functional linear polymers that capture and neutralize a toxic peptide: a comparison with cross-linked nanoparticles

Yusuke Wada, Haejoo Lee, Yu Hoshino, Shunsuke Kotani, Kenneth J. Shea, Yoshiko Miura

Journal of Materials Chemistry B · 2015 · 30 citations · 37 references

Concepts

Abstract

) for a ∼1000 mer linear polymer with 40% tert-butyl group and 20% carboxylic acid. Comparison of the interactions of the LPs and NPs suggested the importance of the flexibility of the polymer chain in order to achieve high binding capacity and affinity.

References

37