Synthesis by a clonal line of rat glial cells of a protein unique to the nervous system

Abstract

Abstract The synthesis of a protein unique to the nervous system, the “S100‐protein,” has been studied in a clonal line of rat glial cells. It has been shown that these cells do not begin to accumulate “S100‐protein” until the cultures enter a phase of density‐dependent inhibition of cell proliferation. Further experiments indicate that the regulation of “S100‐protein” accumulation resides at least in part in an interaction involving the cell surface.