Concepedia

Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

Scott B. Hoyt, Clare London, David J. Gorin, Matthew J. Wyvratt, Michael H. Fisher, Catherine Abbadie, John P. Felix, María L. García, Xiaohua Li, Kathryn A. Lyons,

Bioorganic & Medicinal Chemistry Letters · 2007 · 73 citations · 16 references

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16

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

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Quantitative assessment of tactile allodynia in the rat paw

Sandra R. Chaplan, Flemming W. Bach, J W Pogrel et al. · Journal of Neuroscience Methods · 1994 · 7.9K citations

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An SCN9A channelopathy causes congenital inability to experience pain

James J. Cox, Frank Reimann, Adeline K. Nicholas et al. · Nature · 2006 · 1.6K citations · Full text

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SCN9A Mutations in Paroxysmal Extreme Pain Disorder: Allelic Variants Underlie Distinct Channel Defects and Phenotypes

Caroline Fertleman, Mark D. Baker, Keith A. Parker et al. · Neuron · 2006 · 755 citations · Full text

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Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neurons

Sulayman D. Dib‐Hajj, Anthony M. Rush, T.R. Cummins et al. · Brain · 2005 · 484 citations · Full text

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