Journal of Endocrinology · 1969 · 11 citations · 0 references
MedicineEndocrinologyNeuroscienceEndocrine SurgeryNeuroendocrinologyReproductive EndocrinologyHypothalamic-pituitary AxisHypothalamic-pituitary RegulationNeuroendocrine RegulationPituitary Hormone RegulationPituitary HormonesPituitary SurgeryHypothalamic NeurosecretionHypothalamic Regulation Of ProlactinHypothalamic-pituitary-prolactin AxisNeural Feedback ControlProlactin BiosynthesisProlactin MetabolismProlactin Secretion RegulationWater Drive
SUMMARY The transplanted pituitary is able to trigger water drive in estivating hypophysectomized adult newts up to 140 days after the operation. Both in short-term (30 days) and long-term (140 days) operated animals the grafted pituitary produced significantly more prolactin than in controls. The results indicate that in the estivating crested newt prolactin production is under an inhibitory neural control and that a short feedback control is not exerted by prolactin itself on the grafted pituitary.