Brilliant Blue G improves cognition in an animal model of Alzheimer’s disease and inhibits amyloid-β-induced loss of filopodia and dendrite spines in hippocampal neurons

Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Pascale N. Lacor, Maria C. Buniel, Paul W. Furlow et al. · Journal of Neuroscience · 2007 · 1.2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Oligomeric amyloid β associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

Robert M. Koffie, Melanie Meyer‐Luehmann, Tadafumi Hashimoto et al. · Proceedings of the National Academy of Sciences · 2009 · 842 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

Shaomin Li, Ming Jin, Thomas Koeglsperger et al. · Journal of Neuroscience · 2011 · 657 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

P2X7 Mediates Superoxide Production in Primary Microglia and Is Up-regulated in a Transgenic Mouse Model of Alzheimer's Disease

Lav K. Parvathenani, Svetlana Tertyshnikova, Corinne Greco et al. · Journal of Biological Chemistry · 2003 · 481 citations · Full text

Life Sciences, Neurobiology, Pharmacology +17

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury

Weiguo Peng, Maria Luisa Cotrina, Xiaoning Han et al. · Proceedings of the National Academy of Sciences · 2009 · 425 citations · Full text

Medicine, Neuroscience, Pharmacology +17