All-trans retinoic acid induces p53-depenent apoptosis in human hepatocytes by activating p14 expression via promoter hypomethylation

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.6K citations · Full text

Epigenetic Change, Genetics, Dna Methylation +21

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

Tumor Biology, Medicine, Rapid Degradation +6

ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

Yanping Zhang, Yue Xiong, Wendell G. Yarbrough · Cell · 1998 · 1.6K citations · Full text

Tumor Biology, Cell Regulation, Medicine +9

The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

Jason H. Pomerantz, Nicole Schreiber‐Agus, Nanette J. Liégeois et al. · Cell · 1998 · 1.5K citations · Full text

Tumor Biology, Neutralizes Mdm2, Medicine +6

Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

Frédérique Ponchel, Carmel Toomes, Kieran Bransfield et al. · BMC Biotechnology · 2003 · 373 citations · Full text