Concepedia

Anti-epileptic activity of group II metabotropic glutamate receptor agonists (−)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (−)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795)

Randal X. Moldrich, M Jeffrey, Ardeshir Talebi, Philip M. Beart, Astrid G. Chapman, Brian S. Meldrum

Neuropharmacology · 2001 · 59 citations · 29 references

DOI

Concepts

References

29

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

, , +12

Modification of seizure activity by electrical stimulation: II. Motor seizure

Ronald J. Racine · Electroencephalography and Clinical Neurophysiology · 1972 · 7.2K citations

, , +16

Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740):  A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties

James A. Monn, Matthew J. Valli, Steven M. Massey et al. · Journal of Medicinal Chemistry · 1997 · 393 citations

, , +17

ROLE OF BRAIN NOREPINEPHRINE IN AUDIOGENIC SEIZURE IN THE RAT

Phillip C. Jobe, Albert L. Picchioni, Lincoln Chin · Journal of Pharmacology and Experimental Therapeutics · 1973 · 365 citations

, , +14

The Role of GABA <sub>B</sub> Receptor Activation in Absence Seizures of Lethargic ( <i>lh</i> / <i>lh</i> ) Mice

David A. Hosford, Suzanne Clark, Zhen Cao et al. · Science · 1992 · 360 citations

, , +17