Concepedia

Publication | Open Access

Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma

DOIFull Paper Access

57

Citations

37

References

2014

Year

Robert T. Wicks, Javad Azadi, Antonella Mangraviti, Irma Zhang, Lee Hwang, Avadhut D. Joshi, Hansen Bow, Marianne Hütt-Cabezas, Kristin L. Martin, Michelle A. Rudek,
Neuro-Oncology

Abstract

Intracranial delivery of 3-BrPA and DCA polymer was safe and significantly increased survival in an animal model of glioma, a potential novel therapeutic approach. The combination of intracranial 3-BrPA and TMZ provided a synergistic effect.

References

YearCitations

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