The Arrestin Domain-Containing 3 Protein Regulates Body Mass and Energy Expenditure

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Pere Puigserver, Zhidan Wu, Cheol Won Park et al. · Cell · 1998 · 3.8K citations · Full text

Life Sciences, Molecular Biology, Physiology +16

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

Struan F.A. Grant, Inga Reynisdóttir, Rafn Benediktsson et al. · Nature Genetics · 2006 · 2.3K citations

Medicine, Genetics, Molecular Genetics +16

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki et al. · Nature · 2006 · 2.2K citations · Full text

Life Sciences, Endocrinology, Physiology +14

Effects of Recombinant Leptin Therapy in a Child with Congenital Leptin Deficiency

I. Sadaf Farooqi, Susan A. Jebb, Gill Langmack et al. · New England Journal of Medicine · 1999 · 2K citations · Full text

Medicine, Endocrinology, Pediatrics +17

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

G. Bragi Walters, Daníel F. Guðbjartsson, Valgerður Steinthórsdóttir et al. · Nature Genetics · 2008 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +10