The 650-kDa 12(S)-Hydroxyeicosatetraenoic Acid Binding Complex: Occurrence in Human Platelets, Identification of Hsp90 as a Constituent, and Binding Properties of Its 50-kDa Subunit

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson et al. · Cell · 1995 · 2K citations · Full text

Life Sciences, Biochemistry, Physiology +16

The PPARα–leukotriene B4 pathway to inflammation control

Pallavi R. Devchand, H. J. Keller, Jeffrey M. Peters et al. · Nature · 1996 · 1.4K citations

Life Sciences, Molecular Biology, Pharmacology +12

Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

Sven Hammarström, Mats Hámberg, B Samuelsson et al. · Proceedings of the National Academy of Sciences · 1975 · 590 citations · Full text

Medicine, Biochemistry, Dermatology +17

Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis.

Dean G. Tang, Yong Q. Chen, Kenneth V. Honn · Proceedings of the National Academy of Sciences · 1996 · 336 citations

Life Sciences, Cancer Biology, Oncology +15

Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes.

Roy J. Soberman, Timothy W. Harper, D. J. Betteridge et al. · Journal of Biological Chemistry · 1985 · 178 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +9