Multiple Nevoid Basal-Cell Epithelioma, Jaw Cysts and Bifid Rib

TLDR

A 31‑year‑old woman presented with widespread basal‑cell nevi, corpus callosum agenesis, and dentigerous cysts, illustrating a rare constellation of cutaneous and oral lesions. She received seven years of radiotherapy to the jaw. She subsequently developed a fibrosarcoma that metastasized to the lungs and vertebrae, leading to death, and had a surgically removed ovarian fibroma, a bifid sixth rib, and an unspecified skeletal anomaly. No additional information provided.

Abstract

IN 1951 Binkley and Johnson1 reported the case of a thirty-one-year-old woman with basal-cell nevi, agenesis of the corpus callosum and dental cysts. The skin lesions, appearing in childhood, extended to involve the neck, face, thorax, abdomen, upper arms and back. The jaw lesions, noted when she was about sixteen years of age, were diagnosed as dentigerous cysts. She was given roentgenotherapy to the jaw for seven years. Subsequently, fibrosarcoma developed in this area and metastasized to the lungs and vertebras, resulting in death. A fibroma of the ovary was surgically removed, and bifid sixth rib and absence of the . . .