A heater-integrated transparent microchannel chip for continuous-flow PCR

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

Russell Higuchi, Carita Fockler, Gavin Dollinger et al. · Nature Biotechnology · 1993 · 2.2K citations

Life Sciences, Biotechnology, Molecular Biology +16

Chemical Amplification: Continuous-Flow PCR on a Chip

Martin U. Kopp, Andrew J. de Mello, A. Manz · Science · 1998 · 1.2K citations

Life Sciences, Biotechnology, Microbiology +12

Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification.

Tom Morrison, Janis J. Weis, Carl T. Wittwer · PubMed · 1998 · 966 citations

Life Sciences, Genetics, Molecular Biology +13

Functional Integration of PCR Amplification and Capillary Electrophoresis in a Microfabricated DNA Analysis Device

Adam T. Woolley, Dean Hadley, Phoebe Landre et al. · Analytical Chemistry · 1996 · 728 citations

Engineering, Bioengineering, Biotechnology +16

Integrated System for Rapid PCR-Based DNA Analysis in Microfluidic Devices

Julia Khandurina, Timothy E. McKnight, Stephen C. Jacobson et al. · Analytical Chemistry · 2000 · 538 citations

Engineering, Bioengineering, Molecular Biology +16