SO-CALLED AGENESIA OF THE CORPUS CALLOSUM (CALLOSAL DEFECT)

Abstract

THE MANY and varied concepts of defects, or agenesias, of the corpus callosum will be easily understood by a comparison of two recent papers on this subject. De Morsier and Mozer¹suggested as an etiologic factor a disturbance during the closure of the anterior neuropore, as had previously been proposed by Marchand,²Goldstein³and Ernst.⁴De Morsier and Mozer¹described a second type, in which an embryonal neoplastic agent, a lipoma or an angioma, destroys the corpus callosum (callosal body) during fetal life. Eventually, they claimed that disturbances in the vascularization of the lamina terminalis by the anterior callosal artery during fetal life was another cause. Kirschbaum,⁵on the contrary, suggested porencephaly as a cause of agenesia of the corpus callosum, whereby, in agreement with Yakovlev and Wadsworth,⁶an agenesia of the gyrus cinguli is the causative factor. In my paper presented at